Project name: Biodegradable implants in porous iron obtained by additive manufacturing
Project code: GradImp
Project timeline: 2022 - 2024
Research group: Mechanical Design
Objective
Biodegradable devices have the potential to become successful candidates for temporary medical implant devices, as they are able to degrade in the human body upon tissue healing, reducing the costs of additional removal surgery. To accomplish the challenge of producing such complex structures, an advanced method of additive manufacturing (AM), such as sintered laser melting (SLM) will be used. This new line of research will evaluate the effect of the design of the iron scaffold, produced by additive manufacturing, in the resulting properties, to obtain the suitable characteristics for temporary bone implants. Prototypes will be developed and submitted to cytocompatibility and microbiology assays. The combination of biodegradable iron and additive manufacturing (AM) leads to a revolutionary change of metal implants in many aspects including materials, design, manufacturing, and clinical applications.
Project team
Publications
Mariana Salama, Porous Iron Biodegradable Structures, IST, UL, Jul, 2023
Pedro Nogueira, João Magrinho, M.B.Silva, Augusto Moita de Deus, M. Fátima Vaz, Graded Lattice Structures for Biodegradable Temporary Implants: Computational Evaluation with Two Unit Cell Types, Towards a Smart, Resilient and Sustainable Industry. ISIEA 2023, Jun, 2023
Mariana Salama, Frederico Alves, Luis Reis, Augusto Moita de Deus, M.B.Silva, Catarina Santos, M.J. Carmezim, M. Fátima Vaz, Mechanical and corrosion performance of biodegradable iron porous structures, Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications, 2023
Pedro Nogueira, Kerman Castresana, João Magrinho, M.B.Silva, Augusto Moita de Deus, M. Fátima Vaz, Computational evaluation of the compressive properties of different lattice geometries to be used as temporary implants, Procedia Computer Science, Nov, 2022
Mariana Salama, Frederico Alves, Luis Reis, Augusto Moita de Deus, M.B.Silva, Catarina Santos, M.J. Carmezim, M. Fátima Vaz, Finite element simulations of mechanical behaviour and degradation of iron lattices, MDA 2022, 4th International Conference on Materials Design and Applications, 7-8 July , Jul, 2022
Guilherme Opinião, Manuel Sardinha, Nuno A. Ribeiro, M. Fátima Vaz, Luis Reis, Development of a fused filament fabricated bioabsorbable interference screw for anterior cruciate ligament regeneration, Procedia Structural Integrity, 42, 2022
Mariana Salama, M. Fátima Vaz, Rogério Colaço, Catarina Santos, M.J. Carmezim, Biodegradable Iron and Porous Iron: mechanical properties, degradation behaviour, manufacturing routes and biomedical applications, Journal of Functional Biomaterials , 13, 1-31, 2022
J.C.C. Paiva, Luis Oliveira, M. Fátima Vaz, Sofia Costa-de-Oliveira, Bioengineering Biodegradable Bone Implants as a New Hope to Reduce Device-Associated Infections?A Systematic Review, Bioengineering, 9, 409, 1-35, 2022
Pedro Nogueira, Desenvolvimento de implantes biodegradáveis de ferro poroso obtidos por fabrico aditivo (Development of biodegradable implants in porous iron obtained by additive manufacturing), IST, UL, Work in progress